FEATURED APPLICATION CONTENT

• Rapid Discovery And Characterization Of Monoclonal Antibodies Against The SARS-CoV-2 Delta Spike Protein

  Delve into the intricate workflow employed for the discovery and characterization of monoclonal antibodies (mAbs) targeting the Delta spike protein.

• Proximity Inducers In Drug Discovery - A Perspective On Cooperativity

  Overcoming the limitations of current proximity inducers requires optimizing cooperativity. Learn how enhancing target affinity can lead to smaller, more effective therapeutics with better safety profiles.

• Boost Your Lab's Performance: 3 Ways To Increase Efficiency

  Maximize your research potential by overcoming workflow bottlenecks. This piece explores flexible strategies for increasing throughput and integrating automation seamlessly into your laboratory operations.

• Transfer Of Fed-Batch To Semi-Perfusion Process

  Continuous processes enhance product quality, yield, and cost savings. Explore transitioning a fed-batch process to perfusion using a small batch bioreactor system to optimize cell culture conditions and comparing performances.

• Improve Productivity And Reduce Risk With Biostat® RM

  Discover how a company overcame cell generation challenges by using a system that achieves a seed ratio of 1:120 and saves four days in seed preparation time.

• Extractables And Leachables Assessment For Single-Use Systems

  Efforts to enhance biopharmaceutical manufacturing focus on boosting production capacity sustainably and economically. Explore how optimizing processes with single-use solutions and monitoring leachables ensures product quality.

• Optimizing TFF And SPTFF For High-Concentration mAb Formulations

  Discover the critical role of formulation buffer composition in stabilizing monoclonal antibodies during tangential flow filtration, a process involving ultrafiltration and diafiltration under high pressure and shear forces.

• Selecting A Platform Filter For High Concentration mAbs

  Read more about how Fujifilm Diosynth Biotechnologies evaluated a prime filter with challenging simulant solutions and how the experimental data confirmed superior performance, which demonstrated twice the throughput.

• Downstream Processing Of A Mid-Scale Lentiviral Vector Batch

  Explore how tangential flow filtration (TFF) systems streamline lentivirus purification to enhance efficiency and scalability in CAR-T cell production, which is a crucial advancement in cancer immunotherapy.

• Assuring Multipotency Of Human Mesenchymal Stem Cells (hMSCs)

  Stem cell research has revolutionized tissue repair and regenerative medicine. Discover how mesenchymal stem cells play a key role and offer insights into connective tissue repair, immune response, and inflammatory diseases.

• 2D To 3D Transition Of Mesenchymal Stem Cell Expansion Process

  Discover how transitioning from 2D to 3D culture methods enhances the scalability, yield, and quality of Mesenchymal Stem Cells (MSCs) for therapeutic applications to address critical manufacturing challenges.

• Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines

  Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.