Drug Discovery Online Home Page

Addex Drug-Candidate Effective In Alzheimer's Disease Model

Thu, 02 Sep 2010 13:10:18 GMT

Allosteric modulation company Addex Pharmaceuticals Ltd (SIX: ADXN) announced today that it has observed efficacy in a model of Alzheimer's disease using a recently discovered orally-available drug-candidate. The proprietary molecule specifically inhibits a receptor subtype called the metabotropic glutamate receptor 2 (mGluR2) via negative allosteric modulation (NAM). An Addex mGluR2 NAM is scheduled to enter Phase I clinical testing in healthy volunteers during 2011.

ReproCELL Announces New Line Of Services In Neuronal Research Using Human iPS Cells

Thu, 02 Sep 2010 04:37:00 GMT

ReproCELL, Inc. (CEO: Chikafumi Yokoyama PhD) is pleased to announce a new line of products to be launched in the autumn of 2010, offering neuronal cells derived from human iPS (induced pluripotent stem) cells

Cetero Research Launches Seminar Series On Accelerated Proof-Of-Concept In Drug Development

Fri, 03 Sep 2010 03:34:00 GMT

Cetero Research, the leading early-stage contract research organization (CRO), is launching a series of scientific seminars, "An Accelerated Path to Proof-of-Concept in Drug Development," designed to help pharmaceutical and biotechnology researchers learn the latest innovations in Phase I and IIa clinical trial designs.

Adimab Selected As Technology Pioneer 2011 By World Economic Forum

Wed, 01 Sep 2010 13:05:00 GMT

The World Economic Forum recently announced that Adimab has been selected as a 2011 Technology Pioneer. To be selected as a World Economic Forum Technology Pioneer, a company must be involved in the development of a major technology or innovation and have the potential for long-term impact on business and society

BIOCIUS Life Sciences Expands Contract Research Service With New ADME Assay Analysis

Wed, 01 Sep 2010 12:23:00 GMT

BIOCIUS Life Sciences Inc., developers of the RapidFire high-throughput mass spectrometry system, today announced a new contract research service that expands the in vitro ADME (Absorption, Distribution, Metabolism and Excretion) assays that can be analyzed quickly and efficiently using RapidFire technology

Product Nonconformance Software

Mon, 09 Aug 2010 04:52:00 GMT

The TrackWise nonconformance solution ensures product non-conformances are properly and efficiently handled through an integrated process that tracks and manages the complete process from the initial report, to the investigation process and root cause analysis to any resulting actions and follow up verification of effectiveness.

New Quality Management Software Created Specifically For Small To Medium Size Companies

Mon, 09 Aug 2010 04:47:00 GMT

TrackWise SelectStart is a purpose-built quality management solution created specifically for small to medium size companies across different segments of life science industries.

Cypress Bioscience Announces Agreement To Discontinue Co-Promotion Of Savella With Forest Laboratories

Wed, 04 Aug 2010 08:34:00 GMT

Cypress Bioscience, Inc., a pharmaceutical company engaged in the development of innovative drugs to treat central nervous system disorders, today announced that it is discontinuing its rights under its agreement with Forest Laboratories to co-promote Savella�, its drug for fibromyalgia

New Earth BioMed Launches Natural-Product-Based Cancer Drug Discovery Program

Wed, 04 Aug 2010 04:04:00 GMT

New Earth BioMed, a new 501(c)3 nonprofit corporation, has launched a long-term drug discovery program to identify mixtures of nontoxic plant compounds useful in treating cancer. An estimated 77 percent of approved cancer and anti-infective drugs in the United States are either natural products or are derived from them

Golden Helix Partners With CloudScientific To Provide Genetic Analysis Software In China

Tue, 31 Aug 2010 13:00:00 GMT

Golden Helix, Inc., a global leader in genetic analysis solutions, today announced that it has entered into an agreement with CloudScientific, a Chinese life sciences software company, to act as a distributor of the company's analytic services and proprietary software, the SNP & Variation Suite

TPP Global Development Ltd Enters Into An Agreement With The University Of Edinburgh For Future Drug Development

Tue, 31 Aug 2010 09:27:00 GMT

TPP Global Development Ltd (TPP) announced an agreement with the University of Edinburgh to collaborate on the development of novel pre-clinical intellectual property originated within the University. TPP and the University of Edinburgh will focus on commercialisation opportunities in the areas of nervous system disorders, immunology/inflammation and oncology

Miele PROFile Magazine

Tue, 31 Aug 2010 05:13:00 GMT

Miele's commercial product division, Professional, serves a diverse array of industries. From dental and laboratory to commercial laundry providers, estate homes and shipboard installations, there's literally no boundary Miele can not cross.

KYTHERA And Bayer Dermatology Unit Intendis Enter Licensing And Development Agreement For Adipolytic Agent ATX-101

Mon, 30 Aug 2010 16:30:00 GMT

KYTHERA Biopharmaceuticals, Inc. ("KYTHERA") and Intendis, Bayer HealthCare's dermatology business, today announced that they have entered into a licensing agreement granting Intendis rights to KYTHERA's lead product candidate, ATX-101, outside of the US and Canada.

Application Note: Using A Laboratory Glassware Washer To Perform Pasteurization

Tue, 31 Aug 2010 03:30:00 GMT

Pasteurization is a thermal treatment applied to foods to destroy pathogens. In the food and beverage industry, tunnel washers are often used to pasteurize bottles of beverages in a production line. Within R & D flavors laboratories, new flavors and additives are tested for heat stability prior to being used in new formulations and production. Typically, pasteurization here is performed with a bench top pasteurization system, in a stove-top immersion bath. By Miele Professional

Simulations Plus Launches MedChem Studio

Tue, 03 Aug 2010 12:00:00 GMT

Simulations Plus, Inc., a leading provider of simulation and modeling software for pharmaceutical discovery and development, has announced the launch of its MedChem Studio software for drug discovery

PerkinElmer To Acquire VisEn Medical, Inc.

Tue, 03 Aug 2010 12:00:00 GMT

PerkinElmer, Inc., a global leader focused on the health and safety of people and the environment, recently announced that it has acquired VisEn Medical, Inc., an in vivo molecular imaging technology company based in Bedford, Massachusetts

Five Prime Therapeutics, Inc. Announces Strategic Alliance With GlaxoSmithKline To Discover Innovative Biologics For Skeletal Muscle Disorders

Tue, 03 Aug 2010 18:30:00 GMT

Five Prime Therapeutics, Inc. (FivePrime), a leader in the discovery and development of innovative biologics announced today that it has formed a focused strategic drug discovery alliance with GlaxoSmithKline. This new collaboration gives GSK exclusive access to FivePrime's drug discovery platforms specifically in the areas of sarcopenia, cachexia and other skeletal muscle disorders. Under the terms of the agreement, GSK will receive access to FivePrime's comprehensive proprietary collection of secreted proteins and transmembrane

Pall: provider of filtration, purification and separation technologies

Thu, 28 Aug 2003 13:19:00 GMT

The life sciences industry is both driven and united by its need for speed to market, product reliability and economics. Pall Corporation's leading edge technologies and services play an essential and pivotal role in this industry's ability to achieve these goals...

Vanda Pharmaceuticals Initiates Phase III Clinical Study Aimed At Resetting The Body Clock

Thu, 26 Aug 2010 10:33:00 GMT

Vanda Pharmaceuticals Inc. (Nasdaq: VNDA), today announced it has initiated a Phase III clinical trial to evaluate tasimelteon in patients with Non-24-Hour Sleep Wake Disorder (N24HSWD), a condition experienced primarily by totally blind individuals that results in abnormal night sleep patterns and chronic daytime sleepiness.

Case Study: Introducing Disposable Systems Into Biomanufacturing

Wed, 25 Aug 2010 05:39:00 GMT

Single-use (disposable) systems are being considered and introduced into many biopharmaceutical processes because manufacturers have identified significant benefits they offer over traditional reusable systems. By Mark Fuller and H�l�ne Pora

Article: Applying Good Engineering Practices To The Design Of Single-Use Systems

Wed, 25 Aug 2010 05:21:00 GMT

Significant changes are being incorporated into biopharmaceutical manufacturing processes as a result of drivers such as increasingly strict regulatory demands, reduction of manufacturing costs, and outsourcing to contract manufacturing organizations (CMOs). By Martyn Botterill and Bruce Rawlings

BioScale Announces First Installation Of The ViBE Protein Analysis Workstation

Tue, 24 Aug 2010 12:30:00 GMT

BioScale Inc., an innovative life science company that develops, manufactures and promotes novel analytical tools enabling advancements in protein research, recently announced the first shipment and installation of the ViBET Protein Analysis Workstation at a major Massachusetts-based pharmaceutical company

Simulations Plus Releases GastroPlus Version 7.0

Tue, 24 Aug 2010 12:00:00 GMT

Simulations Plus, Inc., a leading provider of simulation and modeling software for pharmaceutical discovery and development, has announced the launch of Version 7.0 of GastroPlus, the industry's gold standard software for the simulation of drug absorption, pharmacokinetics, and pharmacodynamics

New Toolkit For Docking Released By OpenEye Scientific Software

Tue, 24 Aug 2010 16:20:00 GMT

OpenEye Scientific Software, Inc., the developer of innovative molecular modeling and cheminformatics solutions for drug discovery, announced the first release of the Docking TK as part of the OpenEye Toolkit v1.7.4 release

Instem Announces Global Partnership Agreement With SAS In Life Sciences

Thu, 19 Aug 2010 14:00:00 GMT

Instem, a leading provider of early drug development software solutions, announced recently it has signed a global partnership agreement with SAS, the leader in business analytics software and services. The partnering arrangement enables Instem to more cost effectively license its clients directly for SAS technology embedded within its Provantis preclinical software suite

Antibody Licence Agreement With Cancer Research Technology

Tue, 10 Aug 2010 07:39:00 GMT

Scancell Holdings Plc, the developer of therapeutic cancer vaccines, and Cancer Research Technology Ltd ('CRT') - Cancer Research UK's commercialisation and development arm recently announce that they have signed an agreement under which Scancell has been granted a licence to use a human antibody known as 105AD7.

Video: Tim Tyson, Chairman And CEO, Aptuit

Tue, 06 Jul 2010 19:43:30 GMT

Aptuit To Acquire GSK's Research Operations In Italy. Tim Tyson explains more in this video.

Article: Conducting The Successful European Clinical Trial

Wed, 07 Jul 2010 03:35:00 GMT

Europe has long been an attractive location for pharmaceutical companies seeking to conduct clinical trials. With a population of 491 million, the continent offers an abundance of potential trial sites, experienced investigators, and patient populations, along with governments and local institutions eager to reap the rewards of research activity. By Robert Reekie

FLUOstar Optima Microplate Fluorometer

Thu, 06 Jul 2000 14:43:00 GMT

The FLUOstar OPTIMA incorporates four measurement modes: fluorescence, time-resolved fluorescence, UV/Vis absorbance, luminescence in one microplate reader.The FLUOstar is a workhorse for the life sciences laboratory performing 260/280 assays, bradfords, PicoGreen�, RiboGreen�, single and dual luciferase, FRET, BRET, calcium uptake, cell based assays, and many, many more.

White Paper: Software To Automate The Analysis And Reporting Of Standard Clinical Pharmacokinetic Studies

Tue, 27 Jul 2010 04:50:00 GMT

WinNonlin® AutoPilot™ is a configurable software application for WinNonlin® that automates the creation of presentation-quality tables, graphs, and text that can be directly inserted into documents, such as presentations and reports for regulatory submissions. By Pharsight Corporation

Article: Continuous Manufacturing for Secondary Processes: Leapfrog Time?

Fri, 23 Jul 2010 04:49:00 GMT

Pharmaceutical secondary manufacturing has long stood in stark contrast to the drug discovery end of the business, as well as to other sectors, when it comes to innovation such as continuous manufacturing. By Rebecca Vangenechten and Ivo Backx

Brochure: TrackWise Enterprise Quality Management System

Mon, 07 Jun 2010 07:34:00 GMT

TrackWise is a fully configurable enterprise quality management system (EQMS) that defines, tracks, manages, and reports on all critical quality and compliance processes.

TrackWise Enterprise Quality Management Software Applications

Mon, 07 Jun 2010 05:38:00 GMT

TrackWise from Sparta Systems has been designed to use a centralized database structure, which can hold any number of record types, providing the ability to manage and track all business applications using a single, centralized interface.

Case Study: ISP Technologies Inc. Achieves Integrated Quality Management With Focus On Process Automation

Fri, 04 Jun 2010 04:58:00 GMT

By Sparta Systems, Inc. International Specialty Products Inc. is recognized globally for developing, manufacturing, and supplying innovative specialty ingredients that enhance product performance. The extensive products that it manufactures are used in a wide array of industries, including pharmaceutical, hair care, skin care, coatings and adhesives, specialty biocides, beverage, food ingredients, agrochemical, and oral care.

Case Study: Cangene Converts To Corporate-Wide, Automated Training Management System

Fri, 04 Jun 2010 03:49:00 GMT

Cangene operates in the fiercely competitive and highly regulated biopharmaceutical industry. A highly educated, skilled and productive workforce is crucial to an organization's success. By Sparta Systems

Video: Jeffrey Mazzeo And Jennine Jordan Discuss The Waters® ACQUITY UPLC®H-Class Biosystem

Fri, 25 Jun 2010 04:31:00 GMT

Recently, Web Editor Lori Clapper traveled to Milford, MA for a preview of the Waters ACQUITY UPLC H-Class Bio System. She sat down with Jeannine Jordan, Product Marketing Manager for Waters and Dr. Jeffrey Mazzeo, Waters' Biopharmaceutical Business Director to discuss how the H-Class system came about, and why their natural next step was to create a system "fit to purpose" for the biopharmaceutical market.

GoIndustry DoveBid

Tue, 23 Jun 2009 13:27:00 GMT

We have more than a century of auctioneering experience, which we are now taking into the 21st century to help companies dispose of their surplus assets in markets across the world.

Video: Dr. Tom Wheat Explains The Waters® ACQUITY UPLC® H-Class Bio System

Tue, 22 Jun 2010 20:47:00 GMT

At HPLC 2010, Waters Corporation introduced the newest addition to the ACQUITY UPLC H-Class System, designed specifically for the biopharmaceutical market.

White Paper: EQMS Coexistence In An Enterprise Environment

Fri, 18 Jun 2010 03:34:00 GMT

Quality and IT executives alike face increasing pressure to implement solutions that allow the highest level of holistic control and oversight on the quality of their operations. This pressure is further compounded by the current economic climate, in which companies face constant demand to drive cost out of operations by eliminating redundant technology and supporting infrastructure. By Sparta Systems, Inc.

Used Cozzoli RFPC-80 Liquid Filler

Thu, 10 Jun 2010 06:00:00 GMT

Used Cozzoli RFPC-80 Liquid Filler

White Paper: A Fact-Based View Of The Workforce - Essential To M&A Success

Wed, 19 May 2010 04:01:00 GMT

This whitepaper provides practical guidelines to M&A success relative to the workforce. Specifically, you will learn: workforce risks that impact M&A; an approach to quantify workforce value; and an audit philosophy to assess the workforce. By Kronos Inc.

Article: Managing CMOs With Complementary Capabilities

Mon, 17 May 2010 06:11:00 GMT

After an innovator organization decides to take a candidate drug through to clinical trials, it faces key decisions relating to managing the production and supply of material to the clinic. By Patheon Inc.

Datasheet: Cadence™ Single-Pass Tangential Flow Filtration Modules And Systems

Fri, 09 Apr 2010 04:24:00 GMT

Single-pass TFF is a breakthrough technology that allows direct flow-through concentration with no recirculation of product.

White Paper: From Discovery To Production, Increasing Operational Efficiencies In The Pharmaceutical Industry

Thu, 29 Apr 2010 13:41:00 GMT

The global pharmaceutical industry has been one of the most successful in recent history, and as it matures, the industry is responding to the changes that naturally occur within any market: new technologies disrupting traditional business models, growth of generic competition, and a search for high- growth markets. By Kronos Inc.

High Throughput Purification and Analysis

Mon, 30 Mar 2009 09:19:00 GMT

Within the pharmaceutical industry, there is general consensus that pure and well-characterized compounds are the prerequisite input for biological screening and lead optimization programs. Over the past several years SCYNEXIS has focused on efficiently delivering compounds of proven purity to our MEDCHEM-FACTORY� customers in a cost-effective manner. We have purified over 500,000 compounds to date.

Datasheet: Early Formulation Development

Fri, 26 Feb 2010 05:08:00 GMT

Patheon and Solvias AG have partnered to provide customers with integrated early development services.

Pharmaceutical Analytical Development

Fri, 20 Nov 2009 05:30:00 GMT

Patheon provides analytical development services focused on accelerating the product development cycle. Analytical chemists develop and validate laboratory methodologies for your new pharmaceutical product, monitor its ongoing stability, and support the formulation and clinical manufacturing process all the way through commercialization.

Particulate Filters

Tue, 03 Oct 2006 12:13:52 GMT

Pall particulate filters were especially developed for the strict requirements in biotechnological and pharmaceutical industries and include a variety of filter sheets and modules, filter cartridges, marksman bag filters, and coalescers.